This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
SNF7DC2 antibody, cgi-34 antibody, hspc177 antibody, pnas-2 antibody, vps60 antibody, chmp5 antibody, zgc:64125 antibody, C9orf83 antibody, HSPC177 antibody, PNAS-2 antibody, Vps60 antibody, 2210412K09Rik antibody, AW545668 antibody, RGD1305968 antibody, charged multivesicular body protein 5 S homeolog antibody, charged multivesicular body protein 5b antibody, charged multivesicular body protein 5 antibody, charged multivesicular body protein 5 L homeolog antibody, chromatin modifying protein 5 antibody, chmp5.S antibody, chmp5b antibody, CHMP5 antibody, chmp5.L antibody, chmp5 antibody, Chmp5 antibody
背景
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).