This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SOSTDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-196 amino acids from the C-terminal region of human SOSTDC1.
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.