This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This LDOC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of human LDOC1L.
Mar6 antibody, Mart6 antibody, dJ1033E15.2 antibody, BC058638 antibody, RGD1306472 antibody, retrotransposon Gag like 6 antibody, leucine zipper, down-regulated in cancer 1-like antibody, RTL6 antibody, Rtl6 antibody, LOC100337805 antibody
背景
LDOC1 (Leucine zipper protein downregulated in cancer cells) is a 146 amino acid nuclear protein that contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is downregulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kB (NF-kB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. LDOC1L (Leucine zipper protein down-regulated in cancer cells-like), also known as MART6 (Mammalian retrotransposon-derived protein 6), is a 239 amino acid protein that belongs to the LDOC1 family.