This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This NKX3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-187 amino acids from the C-terminal region of human NKX3-1.
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.