This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SCAND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the C-terminal region of human SCAND1.
The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene.