This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This LRRC16A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1152-1178 amino acids from the C-terminal region of human LRRC16A.
LRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).