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IKK-alpha /IKK-beta 抗体 (pSer180)

适用: 小鼠, 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1531284
发货至: 中国
  • 抗原 See all IKK-alpha /IKK-beta products
    IKK-alpha /IKK-beta
    抗原表位
    • 41
    • 25
    • 25
    • 15
    • 10
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-200, pSer180
    适用
    • 82
    • 61
    • 36
    • 3
    • 3
    • 3
    • 1
    • 1
    小鼠, 人, 大鼠
    宿主
    • 91
    克隆类型
    • 83
    • 8
    多克隆
    标记
    • 23
    • 7
    • 4
    • 4
    • 3
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    • 3
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This IKK-alpha /IKK-beta antibody is un-conjugated
    应用范围
    • 55
    • 41
    • 40
    • 27
    • 17
    • 11
    • 10
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性

    IKK-alpha/beta (Phospho-Ser180/181) Antibody detects endogenous levels of IKK-alpha/beta only when phosphorylated at Ser180/181.

    PhosphorylationH:S180/S181 M:S180/S181 R:S180/S181

    纯化方法
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    纯度
    > 95 %
    免疫原
    The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181.
    亚型
    IgG
  • 应用备注
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
    说明

    Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable at -20°C for at least 1 year.
    有效期
    12 months
  • Hsieh, Hsiao, Hsu, Wang, Sheu: "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." in: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).

  • 抗原
    IKK-alpha /IKK-beta
    别名
    IKK-alpha/beta (IKK-alpha /IKK-beta 产品)
    背景

    Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp

    NCBI Gene Symbol: CHUK

    分子量
    84 kDa
    基因ID
    1147, 3551
    OMIM
    600664
    UniProt
    O15111, O14920
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