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CSK 抗体

CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101334
发货至: 中国
  • 抗原 See all CSK 抗体
    CSK (C-Src tyrosine Kinase (CSK))
    适用
    • 111
    • 58
    • 46
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 100
    • 10
    • 3
    克隆类型
    • 101
    • 11
    单克隆
    标记
    • 53
    • 9
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSK antibody is un-conjugated
    应用范围
    • 102
    • 49
    • 26
    • 26
    • 16
    • 15
    • 12
    • 9
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human CSK
    亚型
    IgG
    Top Product
    Discover our top product CSK Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CSK (C-Src tyrosine Kinase (CSK))
    别名
    CSK (CSK 产品)
    别名
    AW212630 antibody, C-terminal Src kinase antibody, c-src tyrosine kinase antibody, CSK, non-receptor tyrosine kinase antibody, CSK antibody, Csk antibody
    背景
    Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR and B-cell receptor (BCR by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.,CSK, tyrosine-protein kinase CSK,B Cell Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Signal Transduction,CSK
    分子量
    50 kDa
    基因ID
    1445
    UniProt
    P41240
    途径
    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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