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Leptin 抗体 (AA 22-167)

This anti-Leptin antibody is a 兔 多克隆 antibody detecting Leptin in WB 和 IF. Suitable for 人.
产品编号 ABIN1513150
发货至: 中国

Quick Overview for Leptin 抗体 (AA 22-167) (ABIN1513150)

抗原

See all Leptin (LEP) 抗体
Leptin (LEP)

适用

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  • 2
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宿主

  • 182
  • 45
  • 7
  • 5
  • 2
  • 1

克隆类型

  • 195
  • 46
多克隆

标记

  • 132
  • 27
  • 17
  • 9
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  • 3
  • 3
  • 3
  • 3
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  • 1
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This Leptin antibody is un-conjugated

应用范围

  • 163
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  • 1
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 39
    • 16
    • 15
    • 15
    • 9
    • 9
    • 7
    • 5
    • 4
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 22-167

    序列

    VPIQKVQDDT KTLIKTIVTR INDISHTQSV SSKQKVTGLD FIPGLHPILT LSKMDQTLAV YQQILTSMPS RNVIQISNDL ENLRDLLHVL AFSKSCHLPW ASGLETLDSL GGVLEASGYS TEVVALSRLQ GSLQDMLWQL DLSPGC

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 22-167 of human LEP (NP_000221.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Leptin (LEP)

    别名

    LEP

    背景

    This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.,LEP,LEPD,OB,OBS,leptin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,LEP

    分子量

    18 kDa

    基因ID

    3952

    UniProt

    P41159

    途径

    JAK/STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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