This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified.,E2F8,E2F-8,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,Endocrine & Metabolism,Nucleotide metabolism,Molecular processes,E2F8