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DKC1 抗体 (AA 245-514)
DKC1
适用: 人
WB, IHC, IF
宿主: 兔
Polyclonal
unconjugated
DKC1抗体详情
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抗原
See all DKC1 抗体
DKC1
(Dyskeratosis Congenita 1, Dyskerin (DKC1))
抗原表位
All epitopes for DKC1 抗体
AA 245-514
适用
All reactivities for DKC1 抗体
人
宿主
All hosts for DKC1 抗体
兔
克隆类型
All clonalities for DKC1 抗体
多克隆
标记
All conjugates for DKC1 抗体
This DKC1 antibody is un-conjugated
应用范围
All applications for DKC1 抗体
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
序列
ELRRVRSGVM SEKDHMVTMH DVLDAQWLYD NHKDESYLRR VVYPLEKLLT SHKRLVMKDS AVNAICYGAK IMLPGVLRYE DGIEVNQEIV VITTKGEAIC MAIALMTTAV ISTCDHGIVA KIKRVIMERD TYPRKWGLGP KASQKKLMIK QGLLDKHGKP TDSTPATWKQ EYVDYSESAK KEVVAEVVKA PQVVAEAAKT AKRKRESESE SDETPPAAPQ LIKKEKKKSK KDKKAKAGLE SGAEPGDGDS DTTKKKKKKK KAKEVELVSE
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
纯化方法
Affinity purification
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).
亚型
IgG
Alternatives
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使用细节
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应用备注
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid freeze / thaw cycles
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
DKC1目标详情
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抗原
DKC1
(Dyskeratosis Congenita 1, Dyskerin (DKC1))
别名
DKC1 (DKC1 产品 )
别名
CBF5 antibody, DKC antibody, DKCX antibody, NAP57 antibody, NOLA4 antibody, XAP101 antibody, dyskerin antibody, fv62a07 antibody, wu:fa28f10 antibody, wu:fc87a02 antibody, wu:fi24a05 antibody, wu:fv62a07 antibody, zgc:110395 antibody, DKC1 antibody, cbf5 antibody, dkc antibody, nap57 antibody, nola4 antibody, xap101 antibody, BC068171 antibody, Nap57 antibody, AtCBF5 antibody, AtNAP57 antibody, homologue of NAP57 antibody, dyskerin pseudouridine synthase 1 antibody, microRNA 664b antibody, dyskeratosis congenita 1, dyskerin antibody, dyskeratosis congenita 1, dyskerin L homeolog antibody, homologue of NAP57 antibody, DKC1 antibody, MIR664B antibody, dkc1 antibody, dkc1.L antibody, Dkc1 antibody, NAP57 antibody
背景
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.,DKC1,CBF5,DKC,DKCX,NAP57,NOLA4,XAP101,Epigenetics & Nuclear Signaling,RNA Binding,DKC1
分子量
47 kDa/57 kDa
基因ID
1736
UniProt
O60832
途径
Telomere Maintenance
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