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ATF6 抗体 (AA 1-190)

Name: ATF6 抗体 (AA 1-190)
Brand: antibodies-online
SKU: ABIN1512605
Availability: OutOfStock

ATF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using ATF6 antibody. (ATF6 抗体 (AA 1-190))

Immunofluorescence analysis of U2OS cells using Rabbit pAb (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:100 (40x lens). (ATF6 抗体 (AA 1-190))

Immunofluorescence analysis of A549 cell using ATF6 antibody. (ATF6 抗体 (AA 1-190))

Western blot analysis of extracts of various cell lines, using antibody (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at 1:1000 dilution. (ATF6 抗体 (AA 1-190))

Immunohistochemistry of paraffin-embedded Rat ovary using antibody (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:50 (40x lens). (ATF6 抗体 (AA 1-190))

IHC

Immunohistochemistry of paraffin-embedded Human colon using antibody (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:50 (40x lens). (ATF6 抗体 (AA 1-190))

IHC

Immunohistochemistry of paraffin-embedded Mouse kidney using antibody (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:50 (40x lens). (ATF6 抗体 (AA 1-190))

IHC

Immunofluorescence analysis of NIH/3T3 cells using Rabbit pAb (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:100 (40x lens). (ATF6 抗体 (AA 1-190))

Immunofluorescence analysis of PC-12 cells using Rabbit pAb (ABIN3020671, ABIN3020672, ABIN1512605 and ABIN6213659) at dilution of 1:100 (40x lens). (ATF6 抗体 (AA 1-190))

9 images

(3 references)

产品编号 ABIN1512605

发货至: 中国

Datasheet as PDF

抗原 See all ATF6 抗体

ATF6 (Activating Transcription Factor 6 (ATF6))
抗原表位
16

15

12

8

6

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-190
适用
87

43

33

4

4

4

3

3

1

1
人
宿主
77

10

1
兔
Compatible Secondaries
克隆类型
80

8
多克隆
标记
43

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This ATF6 antibody is un-conjugated
应用范围
73

27

27

25

15

15

14

10

7

6

6

3

3

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

序列

MGEPAGVAGT MESPFSPGLF HRLDEDWDSA LFAELGYFTD TDELQLEAAN ETYENNFDNL DFDLDLMPWE SDIWDINNQI CTVKDIKAEP QPLSPASSSY SVSSPRSVDS YSSTQHVPEE LDLSSSSQMS PLSLYGENSN SLSSAEPLKE DKPVTGPRNK TENGLTPKKK IQVNSKPSIQ PKPLLLPAAP

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ATF6 (NP_031374.2).

亚型

IgG
anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibody
ATF6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibody
Verified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibody
ATF6 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibody
ATF6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibody
ATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal 37-1 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 431-530) antibody
ATF6 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Jiang, He, Zhu, Liang, Wang, Lu, Ren, Yi, Xiao, Wang: "Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model." in: Experimental cell research, Vol. 369, Issue 2, pp. 325-334, (2018) (PubMed).

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

He, Xu, Gou, Yuan, Liao, Chen, Fan, Xie, Deng, Zhang, Chen, Zhao: "CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication." in: Frontiers in microbiology, Vol. 8, pp. 2129, (2017) (PubMed).
抗原

ATF6 (Activating Transcription Factor 6 (ATF6))

别名

ATF6 (ATF6 产品)

别名

ATF-6-like antibody, GB16435 antibody, ATF6 antibody, Atf6 antibody, ATF6A antibody, 9130025P16Rik antibody, 9630036G24 antibody, AA789574 antibody, Atf6alpha antibody, ESTM49 antibody, activating transcription factor 6 antibody, uncharacterized LOC412432 antibody, activating transcription factor 6 S homeolog antibody, cyclic AMP-dependent transcription factor ATF-6 alpha antibody, ATF6 antibody, LOC412432 antibody, atf6.S antibody, LOC100122162 antibody, Atf6 antibody

背景

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.,ATF6,ACHM7,ATF6A,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,ATF6

分子量

74 kDa

基因ID

22926

UniProt

P18850

途径

ER-Nucleus Signaling, Unfolded Protein Response