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SIRT1 抗体 (AA 577-590)

SIRT1 适用: 人, 猴 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1493902
发货至: 中国
  • 抗原 See all SIRT1 抗体
    SIRT1 (Sirtuin 1 (SIRT1))
    抗原表位
    • 31
    • 16
    • 16
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 577-590
    适用
    • 146
    • 88
    • 60
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 猴
    宿主
    • 130
    • 20
    • 2
    • 2
    • 1
    山羊
    克隆类型
    • 118
    • 37
    多克隆
    标记
    • 65
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    应用范围
    • 116
    • 50
    • 47
    • 41
    • 39
    • 35
    • 22
    • 22
    • 17
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Human SIRT1. This antibody is expected to recognize both reported isoforms (NP_036370.2, NP_001135970.1).
    预测反应
    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Mouse (93%) Rat (86%).
    纯化方法
    Immunoaffinity purified
    免疫原
    Synthetic peptide C-EKPQEVQTSRNVES from an internal region of human SIRT1 (NP_036370.2, NP_001135970.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Mouse (93%), Rat (86%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • 应用备注
    Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (0.05 - 0.2 μg/mL)

    Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx 120kD band observed in lysates of cell line Jurkat (calculated MW of 81.7kD according to NP_036370.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Cheng et al, Proc Natl Acad Sci U S A. 2003 Sep 16,100(19):10794-9., PMID: 12960381). Recommended concentration: 0.05-0.2 μg/mL.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    SIRT1 (Sirtuin 1 (SIRT1))
    别名
    SIRT1 / Sirtuin 1 (SIRT1 产品)
    别名
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    背景
    Name/Gene ID: SIRT1
    Family: ADP-Ribosyltransferase

    Synonyms: SIRT1, SIR2-like protein 1, SIR2alpha, SIR2L1, Sirtuin 1, Sir2-like 1, Sirtuin type 1, HSIR2, HSIRT1
    基因ID
    23411
    NCBI登录号
    NP_036370, NP_001135970
    UniProt
    Q96EB6
    途径
    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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