FOXD4L1, also known as FOXD5, is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and is thought to play a role in human cancer. FOXD4L1 is a forkhead transcription factor that functions as both a transcriptional activator and repressor and acts upstream of several other neural transcription factors to maintain neural fate, regulate neural plate patterning, and delay the expression of neural differentiation factors.Synonyms: FOXD4L1, Forkhead box protein D4-like 1