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Nicalin 抗体 (C-Term)
NCLN
适用: 人, 小鼠, 大鼠
WB, IF, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
Nicalin抗体详情
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抗原
See all Nicalin (NCLN) 抗体
Nicalin (NCLN)
抗原表位
All epitopes for Nicalin 抗体
C-Term
适用
All reactivities for Nicalin 抗体
人, 小鼠, 大鼠
宿主
All hosts for Nicalin 抗体
兔
克隆类型
All clonalities for Nicalin 抗体
多克隆
标记
All conjugates for Nicalin 抗体
This Nicalin antibody is un-conjugated
应用范围
All applications for Nicalin 抗体
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
特异性
Multiple isoforms of NCLN are known to exist.
交叉反应 (详细)
Species reactivity (tested):Human, Mouse, Rat.
纯化方法
Affinity chromatography purified via peptide column
免疫原
18 amino acid synthetic peptide near the carboxy terminus of Human NCLN
亚型
IgG
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Alternatives
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使用细节
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应用备注
Western blot: 1-2 μg/ml.
Positive Control: Mouse heart tissue lysate.
Immunofluorescence: Start at 2.5 μg/ml.
Immunohistochemistry on Paraffin Sections: Start at 2.5 μg/ml.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
1.0 mg/mL
缓冲液
PBS containing 0.02 % Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Nicalin目标详情
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抗原
Nicalin (NCLN)
别名
Nicalin (NCLN 产品 )
别名
NET59 antibody, RGD1309355 antibody, wu:fb07e09 antibody, wu:fk52a06 antibody, zgc:77236 antibody, 3100002P13Rik antibody, AW120537 antibody, nicalin antibody, NCLN antibody, Bm1_29425 antibody, LOC100280679 antibody, Ncln antibody, ncln antibody
背景
Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer’s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex. Synonyms: NCLN
基因ID
56926
NCBI登录号
NP_064555
UniProt
Q969V3
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