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- 抗原 See all SIVA1 抗体
- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This SIVA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid synthetic peptide near the amino terminus of human SIVA
- Top Product
- Discover our top product SIVA1 Primary Antibody
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anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibody
SIVA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (Internal Region) antibodySIVA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
- 别名
- SIVA1 / SIVA (SIVA1 产品)
- 别名
- CD27BP antibody, SIVA antibody, Siva-1 antibody, Siva-2 antibody, CD27bp antibody, Siva antibody, SIVA1 apoptosis inducing factor antibody, SIVA1, apoptosis-inducing factor antibody, SIVA1 antibody, Siva1 antibody
- 背景
- SIVA plays an important role in the apoptotic pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. SIVA is a small cysteine-rich protein with a unique N-terminal amphipathic helical region, a death domain homology region (DDHR) and a C-terminal cysteine-rich B-box-like or zinc-finger-like structure. The DDHR domain binds to CD27 and induces apoptosis in T cells through a caspase-dependent mitochondrial pathway. SIVA inhibits BCL2L1 isoform Bcl-xL anti-apoptotic activity and inhibits activation of NFk-B and promotes T-cell receptor-mediated apoptosis. SIVA represents a potential therapeutic target for the treatment of neuronal cell death diseases.Synonyms: Apoptosis regulatory protein Siva, CD27-binding protein, CD27BP
- 基因ID
- 10572
- NCBI登录号
- NP_068355
- 途径
- Positive Regulation of Endopeptidase Activity
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