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ZGPAT 抗体 (C-Term)

ZGPAT 适用: 人 WB, IF, EIA 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN1450081
发货至: 中国
  • 抗原 See all ZGPAT 抗体
    ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
    抗原表位
    • 15
    • 5
    • 2
    • 1
    • 1
    C-Term
    适用
    • 25
    • 19
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 24
    • 2
    小鸡
    克隆类型
    • 26
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZGPAT antibody is un-conjugated
    应用范围
    • 25
    • 13
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid synthetic peptide near the carboxy terminus of human ZGPAT
    Top Product
    Discover our top product ZGPAT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))
    别名
    ZGPAT (ZGPAT 产品)
    别名
    zc3h9 antibody, gpatc6 antibody, gpatch6 antibody, zc3hdc9 antibody, GPATC6 antibody, GPATCH6 antibody, KIAA1847 antibody, ZC3H9 antibody, ZC3HDC9 antibody, ZIP antibody, 1500006I01Rik antibody, BC021513 antibody, RGD1310801 antibody, zgc:63730 antibody, zinc finger CCCH-type and G-patch domain containing antibody, zinc finger, CCCH-type with G-patch domain L homeolog antibody, zinc finger, CCCH-type with G-patch domain antibody, zinc finger, CCCH-type with G patch domain antibody, ZGPAT antibody, zgpat.L antibody, zgpat antibody, Zgpat antibody
    背景
    The Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT), is a transcriptional repressor that regulates several cellular pathways including EGFR pathways that are involved in cell proliferation, migration and survival. ZGPAT recruits the Mi-2/NuRD complex and represses the expression of EGFR. ZGPAT is down-regulated in breast carcinomas and its expression is negatively correlated with that of EGFR, suggesting that it may be a potential target for breast cancer therapy. Multiple isoforms of ZGPAT are known to exist, including sZIP, which binds to the Mi-2/NuRD complex but lacks the DNA binding component of full-length ZGPAT, thereby antagonizing transcription repression and growth inhibition by ZGPAT.Synonyms: G patch domain-containing protein 6, GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, Zinc finger CCCH domain-containing protein 9, Zinc finger CCCH-type with G patch domain-containing protein
    基因ID
    84619
    NCBI登录号
    NP_115916
    途径
    EGFR Signaling Pathway
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