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C2orf40 抗体 (C-Term)

C2orf40 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1450064
发货至: 中国
  • 抗原 See all C2orf40 抗体
    C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 35
    • 24
    • 21
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 33
    • 2
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C2orf40 antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    20 amino acid synthetic peptide near the carboxy terminus of Human ECRG4
    亚型
    IgG
    Top Product
    Discover our top product C2orf40 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    C2orf40 (Chromosome 2 Open Reading Frame 40 (C2orf40))
    别名
    Augurin (C2orf40 产品)
    背景
    The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues.. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.Synonyms: C2orf40, ECRG4
    基因ID
    84417
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