BCTL1 antibody, BTCL1 antibody, AI851453 antibody, Btcl1 antibody, C130005O10Rik antibody, RGD1566269 antibody, neuropilin and tolloid like 1 antibody, neuropilin (NRP) and tolloid (TLL)-like 1 antibody, NETO1 antibody, Neto1 antibody
背景
Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.Synonyms: BTCL1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, Neuropilin and tolloid-like protein 1