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- 抗原 See all FAM193B products
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
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抗原表位
- N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM193B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid synthetic peptide near the amino terminus of Human FAM193B
- 亚型
- IgG
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anti-Family with Sequence Similarity 193, Member B (FAM193B) (N-Term) antibody
FAM193B 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
- 别名
- FAM193B (FAM193B 产品)
- 别名
- IRIZIO antibody, Kiaa1931 antibody, family with sequence similarity 193 member B antibody, family with sequence similarity 193, member B antibody, FAM193B antibody, Fam193b antibody
- 背景
- FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.Synonyms: Family with sequence similarity 193 member B, IRIZIO
- 分子量
- 99 kDa
- 基因ID
- 54540
- UniProt
- Q96PV7
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