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- 抗原 See all Selenoprotein K (SELK) 抗体
- Selenoprotein K (SELK)
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Selenoprotein K antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of Human SELK
- 亚型
- IgG
- Top Product
- Discover our top product SELK Primary Antibody
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anti-Selenoprotein K (SELK) (AA 39-91) antibody
SELK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Selenoprotein K (SELK) (AA 32-61) antibodySELK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB32894 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Selenoprotein K (SELK)
- Abstract
- SELK 产品
- 别名
- selenoprotein K antibody, SELENOK antibody
- 背景
- SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited
- 分子量
- 10 kDa
- 基因ID
- 58515
- NCBI登录号
- NP_067060
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