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ZFYVE21 抗体 (N-Term)

This anti-ZFYVE21 antibody is a 兔 多克隆 antibody detecting ZFYVE21 in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1449943
发货至: 中国

Quick Overview for ZFYVE21 抗体 (N-Term) (ABIN1449943)

抗原

See all ZFYVE21 抗体
ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

适用

  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 4
  • 3

克隆类型

  • 6
  • 1
多克隆

标记

  • 7
This ZFYVE21 antibody is un-conjugated

应用范围

  • 7
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    15 amino acid synthetic peptide near the amino terminus of Human ZF21

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

    别名

    ZFYVE21

    背景

    ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Synonyms: Zinc finger FYVE domain-containing protein 21

    基因ID

    79038

    NCBI登录号

    NP_001185882
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