4930459B04Rik antibody, 6330408P11Rik antibody, tty antibody, TTYH1 antibody, ttyh1-A antibody, tweety family member 1 antibody, tweety family member 1 L homeolog antibody, Protein tweety homolog 1 antibody, Ttyh1 antibody, TTYH1 antibody, ttyh1.L antibody, ttyh-1 antibody
背景
TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.Synonyms: Protein tweety homolog 1