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ATG4A 抗体 (C-Term)

ATG4A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449633
发货至: 中国
  • 抗原 See all ATG4A 抗体
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 369-398, C-Term
    适用
    • 65
    • 33
    • 27
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 58
    • 4
    • 2
    • 1
    克隆类型
    • 61
    • 4
    多克隆
    标记
    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4A antibody is un-conjugated
    应用范围
    • 33
    • 21
    • 19
    • 15
    • 14
    • 13
    • 9
    • 6
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide between 369~398 amino acids from the C-term of Human APG4A
    亚型
    Ig Fraction
    Top Product
    Discover our top product ATG4A Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    别名
    Autophagin-2 (ATG4A 产品)
    别名
    apg4a antibody, autl2 antibody, F6E13.27 antibody, APG4A antibody, zgc:111958 antibody, Aut2a antibody, AUTL2 antibody, AI627006 antibody, AV169859 antibody, Apg4a antibody, Atg4al antibody, Autl2 antibody, Atg4a antibody, autophagy related 4A cysteine peptidase L homeolog antibody, autophagy related 4A cysteine peptidase antibody, Peptidase family C54 protein antibody, ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody, autophagy related 4A, cysteine peptidase antibody, atg4a.L antibody, ATG4A antibody, AT2G44140 antibody, atg4a antibody, Atg4a antibody
    背景
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.Synonyms: APG4A, ATG4A, AUT-like 2 cysteine endopeptidase, AUTL2, Autophagy-related cysteine endopeptidase 2, Autophagy-related protein 4 homolog A, Cysteine protease ATG4A
    分子量
    45378 Da
    基因ID
    115201
    NCBI登录号
    NP_443168
    途径
    Autophagy
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