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ICAM1 抗体 (FITC)

ICAM1 适用: 人 FACS 宿主: 小鼠 Monoclonal WK1 FITC
产品编号 ABIN1449268
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    适用
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    小鼠
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    单克隆
    标记
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    This ICAM1 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    Protein A agarose
    免疫原
    Human myeloma cell line (RPMI8226)
    克隆位点
    WK1
    亚型
    IgG1
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS containing 1 % BSA and 0.09 % NaN3.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 / ICAM1 (ICAM1 产品)
    别名
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    物质类
    Viral Protein
    背景
    Intercellular adhesion molecules (ICAMs) are type I transmem brane glycoproteins, which contain 2-9 immunoglobulin-like C2-type domains, and bind to lymphocyte function- associated antigen-1 (LFA-1, also known as a L/ ß 2 or CD11a/CD18). ICAM-1 (CD54) binds to not only LFA-1 but also CD11b/CD18 (Mac-1) and CD11c/CD18. ICAM-1 is also the major receptor for human rhinovirus. ICAM-1 and LFA-1 are involved in the formation of the adhesion ring junction at the immunologic synapse between T cells and antigen presenting cells. ICAM-1 is expressed at low levels on diverse cell types, and is readily induced by activation with proinflammatory cytokines such as IL-1, TNF, IFN- γ , and GM-CSF. ICAM-1 plays a role in both adhesion and extravasation of leukocytes to endothelium during inflammation. Soluble forms of ICAM-1 (sICAM-1) have been detected in a variety of body fluids and correlated with the intensity of the clinical condition of inflammatory and immune disorders. Several studies have provided evidence that sICAM-1 can bind to cell surface ß 2 integrins (CD18), causing reduced adherence of leukocytes to endothelial cells and the accompanying intracellular signaling responses.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    基因ID
    9606
    UniProt
    P05362
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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