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MORC3 抗体

MORC3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 小鼠 Monoclonal 17A9 unconjugated
产品编号 ABIN1449250
发货至: 中国
  • 抗原 See all MORC3 抗体
    MORC3 (MORC Family CW-Type Zinc Finger 3 (MORC3))
    适用
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 8
    • 3
    小鼠
    克隆类型
    • 10
    • 1
    单克隆
    标记
    • 11
    This MORC3 antibody is un-conjugated
    应用范围
    • 10
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects MORC3.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Protein A agarose
    免疫原
    Recombinant human MORC3
    克隆位点
    17A9
    亚型
    IgG1
    Top Product
    Discover our top product MORC3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    MORC3 (MORC Family CW-Type Zinc Finger 3 (MORC3))
    别名
    MORC3 (MORC3 产品)
    别名
    NXP2 antibody, ZCW5 antibody, ZCWCC3 antibody, 1110051N18Rik antibody, AI452146 antibody, BF318192 antibody, D16Jhu32e antibody, Zcwcc3 antibody, sb:cb561 antibody, sb:cb69 antibody, zgc:101052 antibody, fb73c08 antibody, wu:fb73c08 antibody, zgc:162471 antibody, morc3 antibody, MORC family CW-type zinc finger 3 antibody, microrchidia 3 antibody, MORC family CW-type zinc finger 3b antibody, MORC family CW-type zinc finger 3a antibody, MORC family CW-type zinc finger 3 S homeolog antibody, MORC3 antibody, Morc3 antibody, morc3b antibody, morc3a antibody, morc3.S antibody
    背景
    MORC3 { m icr orc hidia (MORC) family CW-type zinc finger 3 , KIAA0136, ZCWCC3 and NXP-2}, is a member of the MORC protein family characterized by the conser ved domains consisting of a GHL (Gyrase B, Hsp90 and MutL)-ATPase domain at the N-terminus, a zinc finger type CW domain containing conserved four cysteines and two tryptophans, a nuclear localization signal (NLS) and coiled-coil domains at the C-terminus. There are four MORC family proteins (MORC1, MORC2, MORC3, and MORC4) in human and five (Morc1, Morc2a, Morc2b, Morc3, and Morc4) in mice. MORC1 is expressed specifically in male germ cells, whereas MORC2 and MORC3 in human are ubiquitously expressed. The autosomal recessive mutation of Morc1 in mice causes the arrest of spermatogenesis early in prophase I of meiosis. Takahashi et al . reported that MORC3 is involved in p53 activation and localization of conditionally localized p53 and constitutively localized Sp100 to promyelocytic leukemia (PML)-nuclear bodies (NBs) through its GHL-ATPase activity. MORC3 is localized in PML-nuclear bodies and entire nucleoplasm except for nucleoli.Synonyms: KIAA0136, MORC family CW-type zinc finger protein 3, ZCWCC3, Zinc finger CW-type coiled-coil domain protein 3
    基因ID
    23515
    NCBI登录号
    NP_056173
    UniProt
    Q14149
    途径
    Maintenance of Protein Location
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