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NUMA1 抗体

NUMA1 适用: 人 WB, IF, IP 宿主: 小鼠 Monoclonal C02142 unconjugated
产品编号 ABIN1449239
发货至: 中国
  • 抗原 See all NUMA1 抗体
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This NUMA1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with human NuMA.
    纯化方法
    Protein A agarose
    免疫原
    Protein fraction extracted from the mitotic chromosome
    克隆位点
    C02142
    亚型
    IgG1
    Top Product
    Discover our top product NUMA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
    别名
    NuMA (NUMA1 产品)
    别名
    NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
    背景
    NuMA (Nuclear Mitotic Apparatus Protein) is involved in maintenance of nuclear structure and in the assembly of the mitotic spindle. During interphase, NuMA is present throughout the nucleus, and during mitosis, it localizes to the spindle. It associates with microtubule motors during mitosis, and plays an essential role in anchoring microtubule ends to the spindle poles. NuMA is an autoantigen, and some individuals with connective tissue disease or other autoimmune disorders have antibodies directed against the NuMA protein. Recent data suggests NuMA (240 kDa) is cleaved to a 180-200 kDa form during apoptosis.Synonyms: NUMA1, Nuclear mitotic apparatus protein 1, SP-H antigen
    分子量
    240 kDa
    基因ID
    4926
    NCBI登录号
    NP_006176
    UniProt
    Q14980
    途径
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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