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Histone H4 抗体

适用: 人, 小鼠, 大鼠, Hamster WB, IF, IP 宿主: 小鼠 Monoclonal C14691 unconjugated
产品编号 ABIN1449238
发货至: 中国
  • 抗原 See all Histone H4 抗体
    Histone H4
    适用
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    人, 小鼠, 大鼠, Hamster
    宿主
    • 354
    • 21
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    小鼠
    克隆类型
    • 329
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    • 1
    单克隆
    标记
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    This Histone H4 antibody is un-conjugated
    应用范围
    • 212
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Histone H4.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat, Hamster
    纯化方法
    Protein A agarose
    免疫原
    Protein fraction extracted from the mitotic chromosome
    克隆位点
    C14691
    亚型
    IgG2b
    Top Product
    Discover our top product Histone H4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    Histone H4
    Abstract
    Histone H4 产品
    背景
    The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-transcriptional modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H4 plays a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes. It has been suggested that acetylated Histone H4 also is involved in heightened activation of the transcription of male X chromosomes, and that Histone H4 stimulates glucose transport activity in rat skeletal muscle.Synonyms: H4/A, H4FA, HIST1H4
    分子量
    11 kDa
    基因ID
    121504
    NCBI登录号
    NP_001029249
    UniProt
    P62805
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