Histone H4 抗体
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- 抗原 See all Histone H4 抗体
- Histone H4
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适用
- 人, 小鼠, 大鼠, Hamster
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Histone H4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with Histone H4.
- 交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat, Hamster
- 纯化方法
- Protein A agarose
- 免疫原
- Protein fraction extracted from the mitotic chromosome
- 克隆位点
- C14691
- 亚型
- IgG2b
- Top Product
- Discover our top product Histone H4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- 抗原
- Histone H4
- Abstract
- Histone H4 产品
- 背景
- The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-transcriptional modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H4 plays a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes. It has been suggested that acetylated Histone H4 also is involved in heightened activation of the transcription of male X chromosomes, and that Histone H4 stimulates glucose transport activity in rat skeletal muscle.Synonyms: H4/A, H4FA, HIST1H4
- 分子量
- 11 kDa
- 基因ID
- 121504
- NCBI登录号
- NP_001029249
- UniProt
- P62805
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