CD52 抗体
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- 抗原 See all CD52 抗体
- CD52
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD52 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with mouse CAMPATH-1/CD52.
- 纯化方法
- Protein G agarose
- 免疫原
- Mouse IL-2R alpha-TGM splenocyte
- 克隆位点
- BTG-2G
- 亚型
- IgG2a
- Top Product
- Discover our top product CD52 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- 抗原
- CD52
- 别名
- CD52 / CAMPATH-1 (CD52 产品)
- 背景
- CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
- 基因ID
- 23833
- NCBI登录号
- NP_038734
- UniProt
- Q64389
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