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BAFF 抗体

TNFSF13B 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1D6 unconjugated
产品编号 ABIN1449224
发货至: 中国
  • 抗原 See all BAFF (TNFSF13B) 抗体
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    适用
    • 117
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    宿主
    • 77
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    小鼠
    克隆类型
    • 88
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    单克隆
    标记
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    This BAFF antibody is un-conjugated
    应用范围
    • 77
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts with human BAFF/BLyS.
    免疫原
    Human BAFF/BLyS transfectant
    克隆位点
    1D6
    亚型
    IgG1
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Protein A agarose, PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    别名
    CD257 / BAFF (TNFSF13B 产品)
    背景
    BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF receptor, BCMA and TACI. The release of soluble BAFF is regulated by IFN-? and to a lesser extent IL-10. BAFF protects B cells from apoptosis and increases the expression of anti-apoptotic proteins Bcl-2 and Bcl-xL.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
    基因ID
    10673
    NCBI登录号
    NP_001139117
    UniProt
    Q9Y275
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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