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DLK1 抗体

This anti-DLK1 antibody is a 大鼠 单克隆 antibody detecting DLK1 in FACS, IHC (p) 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1449213
发货至: 中国

Quick Overview for DLK1 抗体 (ABIN1449213)

抗原

See all DLK1 抗体
DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

适用

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小鼠

宿主

  • 69
  • 8
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  • 1
大鼠

克隆类型

  • 72
  • 12
单克隆

标记

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This DLK1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

24-11-14
  • 特异性

    This antibody reacts with Dlk.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Protein G Agarose Chromatography of hybridoma supernatant

    免疫原

    Pref-1-Fc protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, pH 7.2, None

    储存液

    Azide free

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

    别名

    DLK1

    背景

    Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2

    基因ID

    13386

    NCBI登录号

    NP_034182

    UniProt

    Q09163
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