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EHMT2 抗体 (C-Term)

EHMT2 适用: 人, 小鼠 WB 宿主: 仓鼠 Monoclonal 01-01-14 unconjugated
产品编号 ABIN1449182
发货至: 中国
  • 抗原 See all EHMT2 抗体
    EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))
    抗原表位
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 621-1000, C-Term
    适用
    • 38
    • 17
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 39
    • 2
    仓鼠
    克隆类型
    • 37
    • 4
    单克隆
    标记
    • 29
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EHMT2 antibody is un-conjugated
    应用范围
    • 32
    • 15
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts with both the 165 kDa G9a-L isoform and the 140 kDa G9a-S isoform.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse
    纯化方法
    Protein A agarose
    免疫原
    GST-mouse G9a C-terminal protein (a.a. 621-1000)
    克隆位点
    01-01-14
    亚型
    IgG
    Top Product
    Discover our top product EHMT2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))
    别名
    BAT8 (EHMT2 产品)
    背景
    G9a (BAT8, NG36) is a major histone methyltransferase that acts by adding a methyl group to the Lys9 amino acid on histone H3 proteins. Methylation of Lys9 on histone H3 is important for the regulation of the expression of crucial genes during embryogenesis. Methylation of Lys9 may also play a role in tumorigenesis, since deregulation of histone H3 Lys9 methylation in G9a-deficient cells induces the expression of Mage-2a, a tumor-specific protein whose function is unknown. The 165 kDa G9a protein has an unusual structure, containing 24 contiguous glutamate residues in the N-terminus and 6 contiguous copies of a 33-amino acid ankyrin repeat in the C-terminus. The presence of the ankyrin repeats suggest that G9a may be involved in intracellular protein-protein interactions. G9a is expressed in monocytic, macrophage, hepatocyte, T-cell, B-cell, epithelial, and promyelocytic cell lines.Synonyms: C6orf30, EHMT2, Euchromatic histone-lysine N-methyltransferase 2, H3 lysine-9 specific 3, H3-K9-HMTase 3, HLA-B-associated transcript 8, Histone H3-K9 methyltransferase 3, Histone-lysine N-methyltransferase, KMT1C, Lysine N-methyltransferase 1C, NG36, Protein G9A
    基因ID
    110147
    NCBI登录号
    NP_665829
    UniProt
    Q9Z148
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