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SF3B1 抗体

SF3B1 适用: 人, 小鼠, Hamster WB 宿主: 小鼠 Monoclonal 1A5 unconjugated
产品编号 ABIN1449178
发货至: 中国
  • 抗原 See all SF3B1 抗体
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    适用
    • 50
    • 35
    • 29
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, Hamster
    宿主
    • 62
    • 3
    小鼠
    克隆类型
    • 48
    • 17
    单克隆
    标记
    • 36
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3B1 antibody is un-conjugated
    应用范围
    • 52
    • 21
    • 19
    • 13
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts with Sap155.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Hamster
    纯化方法
    Protein A agarose
    免疫原
    Recombinant mouse Sap155
    克隆位点
    1A5
    亚型
    IgG2b
    Top Product
    Discover our top product SF3B1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    别名
    SF3B1 / SAP155 (SF3B1 产品)
    背景
    SF3 is a U2 snRNP-associated protein complex essential for spliceosome assembly and splicing catalysis of the major spliceosome. SF3 contains the Spliceosome-Associated Proteins, SAP 49, 130, 145, and 155. SAP155/Sf3b1 is an essential subunit of the U2 snRNP for mRNA splicing and has also been identified in the minor (U12-dependent) spliceosome. SAP155 interacts with the mammalian PcG (Polycomb group) proteins, Mel18 and Ring1B by the yeast two-hybrid system. SAP155 contains numerous Cdk consensus phosphorylation sites in its N terminus and is phosphorylated prior to catalytic step II of the splicing pathway. SAP155 serves as a substrate for cyclin E-cdk2 in vitro, suggesting that pre-mRNA splicing may be linked to the cell cycle machinery in mammalian cells.Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit, SAP 155, SAP-155, SF3b155, Spliceosome-associated protein 155, Splicing factor 3B subunit 1
    基因ID
    23451
    NCBI登录号
    NP_036565
    UniProt
    O75533
    途径
    Chromatin Binding
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