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Connexin 43/GJA1 抗体 (C-Term)

Name: Connexin 43/GJA1 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN1440034
Availability: OutOfStock

GJA1 适用: 人, 大鼠, 小鼠, 犬, 猴, Cow, 兔, 小鸡, 豚鼠, Pig, 马, 绵羊, Hamster, 山羊, Avian, Cat, 驴 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

Endogenous CX43 detcted at 1/1000 dilution; Iysate at 100 µg and rabbit polyclonal to goat lgG (HRP) at 1/10,000 dilution. (Connexin 43/GJA1 抗体 (C-Term))

Immunohistochemistry (IHC) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody (ABIN1440034) (Connexin 43/GJA1 抗体 (C-Term))

IHC

Immunostaining of primary RPE cells With CX43 Ab at 1/100 dilution. (Connexin 43/GJA1 抗体 (C-Term))

ISt

Immunofluorescence (IF) image for anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody (ABIN1440034) (Connexin 43/GJA1 抗体 (C-Term))

IHC

9 images

(3 references)

产品编号 ABIN1440034

发货至: 中国

Datasheet as PDF

抗原 See all Connexin 43/GJA1 (GJA1) 抗体

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
抗原表位
19

16

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12

8

7

7

7

7

4

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3

2

2

2

2

2

2

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2

1

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C-Term
适用
131

87

84

30

10

9

8

7

6

6

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3

3

2

2

2

1

1

1

1

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1
人, 大鼠, 小鼠, 犬, 猴, Cow, 兔, 小鸡, 豚鼠, Pig, 马, 绵羊, Hamster, 山羊, Avian, Cat, 驴
宿主
129

6

2

1
山羊
Compatible Secondaries
克隆类型
131

6
多克隆
标记
78

7

4

4

4

4

4

4

3

3

3

3

2

2

2

1

1

1

1

1

1

1

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1

1

1
This Connexin 43/GJA1 antibody is un-conjugated
应用范围
95

55

50

23

19

16

13

13

10

9

6

5

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

特异性

Detects endogenous levels of total connexin 43.

产品特性

Gap junction protein, alpha 1, 43  kDa

纯化方法

epitope affinity purified

免疫原

Purified recombinant peptide derived from within residues 230 aa to the C-terminus of rat CX43 produced in E. coli.

亚型

IgG
anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 310-390) antibody
GJA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (pSer368) antibody
GJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 107-138) antibody
GJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 351-367) antibody
GJA1 适用: 人, 大鼠, 小鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 211-260) antibody
GJA1 适用: 人, 大鼠, 小鼠, 犬 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 244-382) antibody
GJA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibody
GJA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (C-Term) antibody
GJA1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (AA 233-382) antibody
GJA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Gap Junction Protein, alpha 1, 43kDa (GJA1) (N-Term) antibody
GJA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 兔, 豚鼠, 斑马鱼, 马, 绵羊 WB 宿主: 兔 Polyclonal unconjugated

限制

仅限研究用
浓度

4 mg/mL

缓冲液

Polyclonal antibody supplied as a 200 µL (4 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

注意事项

The antibody solution should be gently mixed before use.

储存条件

4 °C,-20 °C

储存方法

For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
Martins-Marques, Pinho, Zuzarte, Oliveira, Pereira, Sluijter, Gomes, Girao: "Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin." in: Journal of extracellular vesicles, Vol. 5, pp. 32538, (2016) (PubMed).

Martins-Marques, Anjo, Pereira, Manadas, Girão: "Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 11, pp. 3040-55, (2016) (PubMed).

Ribeiro-Rodrigues, Catarino, Marques, Ferreira, Martins-Marques, Pereira, Girão: "AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 11, pp. 4629-41, (2015) (PubMed).
抗原

Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

别名

CX43 (GJA1 产品)

别名

AVSD3 antibody, CX43 antibody, DFNB38 antibody, GJAL antibody, HLHS1 antibody, HSS antibody, ODDD antibody, Cx43 antibody, AU042049 antibody, AW546267 antibody, Cnx43 antibody, Cx43alpha1 antibody, Gja-1 antibody, Npm1 antibody, connexin43 antibody, cx43a1 antibody, gja1 antibody, zfCx43.3 antibody, connexin 43 antibody, gja1-A antibody, cx43 antibody, gjal antibody, oddd antibody, dfnb38 antibody, gap junction protein alpha 1 antibody, gap junction protein, alpha 1 antibody, connexin 43 antibody, gap junction protein alpha 1 L homeolog antibody, CONNEXIN 43 protein antibody, GJA1 antibody, Gja1 antibody, cx43 antibody, gja1.L antibody, gja1 antibody, CONNEXIN 43 antibody

背景

Cx43 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. This protein is the major protein of gap junctions in embryonic development and in the heart that are thought to have a crucial role in the synchronized contraction of the heart.
Synonyms: AVSD3, CX43, DFNB38, gap junction protein, alpha 1, 43kDa, GJA1, GJAL HSS, HLHS1, ODDD antibody.
Ensembl identifier: ENSG00000152661

途径

MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization