IFI35 抗体 (PE-Cy7)
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- 抗原 See all IFI35 抗体
- IFI35 (Interferon-Induced Protein 35 (IFI35))
- 适用
- 人, 小鼠, 大鼠, Pig, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IFI35 antibody is conjugated to PE-Cy7
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human IFI35
- 亚型
- IgG
- Top Product
- Discover our top product IFI35 Primary Antibody
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- 应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IFI35 (Interferon-Induced Protein 35 (IFI35))
- 别名
- IFI35 (IFI35 产品)
- 别名
- IFI35 antibody, IFP35 antibody, 2010008K16Rik antibody, AW986054 antibody, ifi-35 antibody, interferon induced protein 35 antibody, interferon-induced protein 35 antibody, IFI35 antibody, ifi35 antibody, Ifi35 antibody
- 背景
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Synonyms: I 35, i-35, I35, P 35, P35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein.
Background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events.
- 分子量
- 31kDa
- 基因ID
- 3430
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