ENKUR 抗体 (Cy5)
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- 抗原 See all ENKUR 抗体
- ENKUR (Enkurin, TRPC Channel Interacting Protein (ENKUR))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ENKUR antibody is conjugated to Cy5
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C10orf63/Enkurin
- 亚型
- IgG
- Top Product
- Discover our top product ENKUR Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ENKUR (Enkurin, TRPC Channel Interacting Protein (ENKUR))
- 别名
- C10orf63 (ENKUR 产品)
- 别名
- C10orf63 antibody, 4933434I06Rik antibody, AU016229 antibody, enkurin, TRPC channel interacting protein antibody, ENKUR antibody, Enkur antibody
- 背景
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Synonyms: DKFZp781F21103, Chromosome 10 open reading frame 63, ENKUR, Enkurin, ENKUR_HUMAN.
Background: Enkurin is a 256 amino acid adapter protein that brings signal transduction proteins and transient receptor potential canonical (TRPC) cation channels into contact. Localizing to the acrosomal crescent and flagellar principal piece of sperm, Enkurin contains one IQ domain which it uses to bind CaM (calmodulin). Enkurin is highly expressed in testis and vomeronasal organ, but is also found at lower levels in brain, ovary, heart and lung. The gene encoding Enkurin maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
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