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ANKRD50 抗体 (Cy3)

ANKRD50 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1422323
发货至: 中国
  • 抗原 See all ANKRD50 products
    ANKRD50 (Ankyrin Repeat Domain 50 (ANKRD50))
    适用
    • 23
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    人, 小鼠, 大鼠
    宿主
    • 23
    克隆类型
    • 22
    多克隆
    标记
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    This ANKRD50 antibody is conjugated to Cy3
    应用范围
    • 23
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ANKRD50
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ANKRD50 (Ankyrin Repeat Domain 50 (ANKRD50))
    别名
    ANKRD50 (ANKRD50 产品)
    别名
    RGD1311665 antibody, AI662170 antibody, E430012K20Rik antibody, mKIAA1223 antibody, mKIAA3019 antibody, ankyrin repeat domain 50 antibody, ANKRD50 antibody, Ankrd50 antibody
    背景

    Synonyms: ANKRD50, Ankyrin repeat domain 50, Ankyrin repeat domain-containing protein 50, ANR50_HUMAN, KIAA1223.

    Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD50 (ankyrin repeat domain 50) is a 1,429 amino acid phosphoprotein that contains nineteen ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly and mosquito, ANKRD50 is encoded by a gene that maps to human chromosome 4q28.1. Chromosome 4 represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which encodes an expanded glutamine tract in cases of Huntington's disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also linked to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

    基因ID
    57182
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