ANKLE2 抗体 (Cy3)
Quick Overview for ANKLE2 抗体 (Cy3) (ABIN1422275)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ANKLE2
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亚型
- IgG
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anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (AA 350-450) antibody
ANKLE2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (Internal Region) antibodyANKLE2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 小鸡 Polyclonal unconjugated
anti-Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2) (AA 864-913) antibodyANKLE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ANKLE2 (Ankyrin Repeat and LEM Domain Containing 2 (ANKLE2))
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别名
- ANKLE2
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背景
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Synonyms: ANKL2_HUMAN, ANKLE 2, ANKLE2, ankyrin repeat and LEM domain containing 2, Ankyrin repeat and LEM domain-containing protein 2, LEM domain containing 7, LEMD 7, LEMD7.
Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
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基因ID
- 23141
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UniProt
- Q86XL3
抗原
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