C21ORF45 抗体 (Cy3)
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- 抗原 See all C21ORF45 (MIS18A) 抗体
- C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C21ORF45 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FASP1/C21orf45
- 亚型
- IgG
- Top Product
- Discover our top product MIS18A Primary Antibody
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anti-MIS18 Kinetochore Protein Homolog A (MIS18A) (N-Term) antibody
MIS18A 适用: 人, 大鼠, 兔, Cow, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-MIS18 Kinetochore Protein Homolog A (MIS18A) (N-Term) antibodyMIS18A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
- 别名
- FASP1 (MIS18A 产品)
- 别名
- B28 antibody, C21orf45 antibody, C21orf46 antibody, FASP1 antibody, MIS18alpha antibody, hMis18alpha antibody, 2610039C10Rik antibody, 2810018N07Rik antibody, RGD1310778 antibody, MIS18 kinetochore protein A antibody, MIS18A antibody, Mis18a antibody
- 背景
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Synonyms: B28, C21orf46, FASP1, hMis18alpha, MaFF interacting protein, MAFIP, MIS18A, Protein Mis18 alpha, MS18A_HUMAN.
Background: Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.
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