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C18orf1 抗体 (AA 1-50) (Cy5)

C18orf1 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1421748
发货至: 中国
  • 抗原 See all C18orf1 抗体
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    AA 1-50
    适用
    • 22
    • 20
    • 20
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 20
    • 2
    克隆类型
    • 22
    多克隆
    标记
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C18orf1 antibody is conjugated to Cy5
    应用范围
    • 22
    • 12
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human C18orf1
    亚型
    IgG
    Top Product
    Discover our top product C18orf1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    别名
    C18orf1 (C18orf1 产品)
    别名
    C18orf1 antibody, 8230401C20Rik antibody, A430083H02 antibody, A430108L08Rik antibody, D18Ertd653e antibody, D330030L18Rik antibody, low density lipoprotein receptor class A domain containing 4 antibody, LDLRAD4 antibody, Ldlrad4 antibody
    背景

    Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4

    Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

    基因ID
    753
    UniProt
    O15165
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