EPR1 抗体 (Cy7)
-
- 抗原 See all EPR1 抗体
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This EPR1 antibody is conjugated to Cy7
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EPR1
- 亚型
- IgG
- Top Product
- Discover our top product EPR1 Primary Antibody
-
anti-Early-Phytochrome-Responsive1 (EPR1) (AA 308-337) antibody
EPR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- EPR1 (Early-Phytochrome-Responsive1 (EPR1))
- 别名
- EPR1 (EPR1 产品)
- 背景
-
Synonyms: Effector cell peptidase receptor 1, Effector cell protease receptor 1, EPR 1, EPR1, EPR-1.
Background: Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
- 基因ID
- 8475
- 途径
- Apoptosis, Cell Division Cycle
-
