LYL1 抗体 (AA 151-250) (Cy3)
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- 抗原 See all LYL1 抗体
- LYL1
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抗原表位
- AA 151-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LYL1 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human LYL1
- 亚型
- IgG
- Top Product
- Discover our top product LYL1 Primary Antibody
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anti-LYL1 (LYL1) (AA 1-280) antibody
LYL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-LYL1 (LYL1) (N-Term) antibodyLYL1 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-LYL1 (LYL1) (AA 212-244) antibodyLYL1 适用: 人 WB 宿主: 兔 Polyclonal RB54126 unconjugated
anti-LYL1 (LYL1) (AA 35-84) antibodyLYL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LYL1
- 别名
- LYL1 (LYL1 产品)
- 别名
- bHLHa18 antibody, Lyl-1 antibody, LYL1, basic helix-loop-helix family member antibody, lymphoblastomic leukemia 1 antibody, LYL1 antibody, Lyl1 antibody
- 背景
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Synonyms: Lyl1; Lymphoblastic leukemia derived sequence 1; Protein lyl 1.
Background: The Lyl1 gene encodes a basic helixloophelix transcription factor involved in T-cell acute lymphoblastic leukemia. The expression of Lyl1 is at higher levels in the majority of cases of acute myeloblastic leukemia (AML) or myelodysplastic syndrome when compared to normal bone marrow. Lyl1 is highly expressed in most AML cell lines.Lyl-1, TAL1 and TAL2 are part of a family of basic helix-loop-helix (bHLH) proteins implicated in T cell acute leukemia. TAL1, also designated SCL, is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. TAL2 is a protein involved in T cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and T cell receptor chain genes. TAL2 includes a helix-loop-helix protein dimerization and DNA-binding domain that is homologous to TAL1 and Lyl-1 proto-oncogenes. Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein. Endogenous Lyl-1 exists in complex with E2å proteins. Lyl-1 and E2å protein can form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. Lyl-1 is involved in a chromosomal aberration which causes a form of T cell acute lymphoblastic leukemia (T-ALL).
- 基因ID
- 4066
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