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SLITRK2 抗体 (AA 311-410) (Cy3)

SLITRK2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1412193
发货至: 中国
  • 抗原 See all SLITRK2 抗体
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-410
    适用
    • 48
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    宿主
    • 48
    克隆类型
    • 48
    多克隆
    标记
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLITRK2 antibody is conjugated to Cy3
    应用范围
    • 43
    • 26
    • 12
    • 12
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLITRK2
    亚型
    IgG
    Top Product
    Discover our top product SLITRK2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
    别名
    SLITRK2 (SLITRK2 产品)
    别名
    slitrk2 antibody, CXorf2 antibody, SLITL1 antibody, A930040J07 antibody, RGD1561361 antibody, SLIT and NTRK-like family, member 2 antibody, SLIT and NTRK like family member 2 antibody, SLITRK2 antibody, slitrk2 antibody, Slitrk2 antibody
    背景

    Synonyms: CXorf2, KIAA1854, SLIK2_HUMAN, SLIT and NTRK like protein 2, SLIT and NTRK-like protein 2, SLITL1, SLITRK 2, Slitrk2.

    Background: SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK2 (SLIT and NTRK-like protein 2) is a 845 amino acid single-pass type I membrane protein that contains 14 LRR (leucine-rich) repeats and is expressed in neural tissues, with highest levels found in adult cerebral cortex. Overexpression of SLITRK2 leads to inhibition of unipolar neurites in cultured cells, suggesting that it suppresses neurite outgrowth. Inhibitory activity of SLITRK2 is localized to its C-terminal intracellular domain and without this region the protein induces neurite outgrowth. Variants in the gene encoding SLITRK2 may contribute to the development of bipolar disorder, autism spectrum disorder and schizophrenia. There are two isoforms of SLITRK2 that are produced as a result of alternative splicing events.

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