TTBK2 抗体 (AA 1151-1244) (HRP)
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- 抗原 See all TTBK2 抗体
- TTBK2 (tau Tubulin Kinase 2 (TTBK2))
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抗原表位
- AA 1151-1244
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTBK2 antibody is conjugated to HRP
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TTBK2/SCA11
- 亚型
- IgG
- Top Product
- Discover our top product TTBK2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TTBK2 (tau Tubulin Kinase 2 (TTBK2))
- 别名
- TTBK2/SCA11 (TTBK2 产品)
- 别名
- ttbk antibody, MGC146331 antibody, 2610507N02Rik antibody, AI326283 antibody, B930008N24Rik antibody, TTK antibody, Ttbk antibody, Ttbk1 antibody, mKIAA0847 antibody, SCA11 antibody, TTBK antibody, tau tubulin kinase 2 antibody, TTBK2 antibody, ttbk2 antibody, Ttbk2 antibody
- 背景
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Synonyms: TTBK2/SCA11 Tau tubulin kinase 2, Spinocerebellar ataxia 11, Tau tubulin kinase 2, Tau-tubulin kinase 2, TTBK, TTBK 2, TTBK1, TTBK2 , TTBK2_HUMAN, TTK, KIAA0847, mKIAA0847, SCA11.
Background: SCA11 is a 1,244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family. The SCA11 gene, comprising of 16 exons, produces a 5.6-kb transcript in which the longest open reading frame is 3,732 nucleotides. Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA). It is a relatively benign, late-onset, slowly progressive neurologic disorder. The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation. Existing as three alternatively spliced isoforms, the SCA11 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 15q15.2.
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