DGCR6 抗体 (AA 112-180) (Cy5)
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- 抗原 See all DGCR6 抗体
- DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))
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抗原表位
- AA 112-180
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DGCR6 antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DGCR6
- 亚型
- IgG
- Top Product
- Discover our top product DGCR6 Primary Antibody
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anti-DiGeorge Syndrome Critical Region Gene 6 (DGCR6) (AA 1-220) antibody
DGCR6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DGCR6 (DiGeorge Syndrome Critical Region Gene 6 (DGCR6))
- 别名
- DGCR6 (DGCR6 产品)
- 别名
- AU044152 antibody, DGCR6 antibody, DKFZp459P114 antibody, DGCR6L antibody, zgc:101841 antibody, DiGeorge syndrome critical region gene 6 antibody, protein DGCR6 antibody, DiGeorge syndrome critical region gene 6 S homeolog antibody, DGCR6 antibody, Dgcr6 antibody, LOC458642 antibody, dgcr6.S antibody, dgcr6 antibody
- 背景
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Synonyms: DGCR 6, DGCR6 protein, DiGeorge syndrome critical region 6, DiGeorge syndrome critical region gene 6, DGCR6_HUMAN.
Background: Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin ?1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome, a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt_ lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.
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