DISP2 抗体 (AA 1101-1200) (Cy3)
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- 抗原 See all DISP2 抗体
- DISP2 (Dispatched Homolog 2 (DISP2))
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抗原表位
- AA 1101-1200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DISP2 antibody is conjugated to Cy3
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DISP2
- 亚型
- IgG
- Top Product
- Discover our top product DISP2 Primary Antibody
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anti-Dispatched Homolog 2 (DISP2) (AA 1101-1200) antibody
DISP2 适用: 人 IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DISP2 (Dispatched Homolog 2 (DISP2))
- 别名
- DISP2 (DISP2 产品)
- 别名
- DISP2 antibody, DISPB antibody, HsT16908 antibody, AI840597 antibody, B230210L08Rik antibody, DispB antibody, mKIAA1742 antibody, dispatched RND transporter family member 2 antibody, dispatched RND tramsporter family member 2 antibody, dispatched homolog 2 (Drosophila) antibody, DISP2 antibody, Disp2 antibody
- 背景
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Synonyms: DISPB, HsT16908, Protein dispatched homolog 2, DISP2, KIAA1742
Background: DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.
- 基因ID
- 85455
- UniProt
- A7MBM2
- 途径
- Hedgehog Signaling
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