Nogo B Receptor 抗体 (AA 167-210) (Cy3)
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- 抗原 See all Nogo B Receptor (NUS1) 抗体
- Nogo B Receptor (NUS1)
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抗原表位
- AA 167-210
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nogo B Receptor antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NGBR/Nogo B receptor
- 亚型
- IgG
- Top Product
- Discover our top product NUS1 Primary Antibody
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anti-Nogo B Receptor (NUS1) (AA 151-200) antibody
NUS1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Nogo B Receptor (NUS1)
- 别名
- NGBR/Nogo B receptor (NUS1 产品)
- 别名
- C6orf68 antibody, MGC:7199 antibody, NgBR antibody, TANGO14 antibody, 1600027K07Rik antibody, AU019165 antibody, AW538011 antibody, BC003223 antibody, D10Ertd438e antibody, NUS1 dehydrodolichyl diphosphate synthase subunit antibody, NUS1 antibody, Nus1 antibody
- 背景
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Synonyms: C6orf68, NGBR, nuclear undecaprenyl pyrophosphate synthase 1 homolog, NUS1, NGBR_HUMAN, Dehydrodolichyl diphosphate synthase complex subunit NUS1, Cis-prenyltransferase subunit NgBR, Nogo-B receptor.
Background: Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NgBR (Nogo-B receptor), also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B. Through this interaction, NgBR is involved in the regulation of vascular remodeling and angiogenesis. NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization. Knockdown of NgBR mRNA leads to decreased NPC2 levels, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing.
- 基因ID
- 116150
- UniProt
- Q96E22
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