CREB3L3 抗体 (AA 201-300) (Cy3)
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- 抗原 See all CREB3L3 抗体
- CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
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抗原表位
- AA 201-300
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CREB3L3 antibody is conjugated to Cy3
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CREB-H
- 亚型
- IgG
- Top Product
- Discover our top product CREB3L3 Primary Antibody
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anti-cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3) (AA 244-274) antibody
CREB3L3 适用: 人 WB 宿主: 兔 Polyclonal RB53691 unconjugated
anti-cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3) (Internal Region) antibodyCREB3L3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3) (AA 371-460) antibodyCREB3L3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))
- 别名
- CREB-H/CREB3L3 (CREB3L3 产品)
- 别名
- CREB-H antibody, CREBH antibody, BC010786 antibody, D10Bur1e antibody, creb3l3a antibody, creb3l3b antibody, si:dkey-110c1.2 antibody, wu:fc88h05 antibody, zgc:112279 antibody, cAMP responsive element binding protein 3 like 3 antibody, cAMP responsive element binding protein 3-like 3 antibody, cAMP responsive element binding protein 3-like 3a antibody, CREB3L3 antibody, Creb3l3 antibody, creb3l3a antibody
- 背景
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Synonyms: cAMP responsive element binding protein 3 like 3, cAMP responsive element-binding protein 3 like protein 3, CREB H, CREB/ATF family transcription factor, CREBH, Cyclic AMP responsive element binding protein 3 like protein 3, cAMP-responsive element-binding protein 3-like protein 3, HYST1481, MGC126553, MGC126557, Transcription factor CREB H, CR3L3_HUMAN.
Background: CREB3L3 is a 461 amino acid single-pass type II membrane protein that localizes to the endoplasmic reticulum (ER) and, in response to ER stress, is cleaved and translocated to the nucleus. Expressed exclusively in liver, CREB3L3 functions as a transcription factor that, during ER stress, is thought to activate genes that are involved in both the unfolded protein response and the acute phase response (APR). Additionally, CREB3L3 is underexpressed in hepatocellular carcinoma, suggesting a possible role as a tumor suppressor. CREB3L3 functions as a dimer and contains one leucine zipper domain, a KDEL-like sequence and a bZIP domain, through which it conveys its DNA binding ability. Three isoforms of CREB3L3 exist due to alternative splicing events.
- 途径
- Thyroid Hormone Synthesis
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