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SH3TC2 抗体 (AA 851-950) (Cy3)

SH3TC2 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN1407879
发货至: 中国
  • 抗原 See all SH3TC2 抗体
    SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))
    抗原表位
    • 14
    • 5
    • 1
    • 1
    AA 851-950
    适用
    • 27
    • 1
    宿主
    • 27
    克隆类型
    • 27
    多克隆
    标记
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3TC2 antibody is conjugated to Cy3
    应用范围
    • 15
    • 12
    • 12
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SH3TC2
    亚型
    IgG
    Top Product
    Discover our top product SH3TC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SH3TC2 (SH3 Domain and Tetratricopeptide Repeats 2 (SH3TC2))
    别名
    SH3TC2 (SH3TC2 产品)
    别名
    CMT4C antibody, MNMN antibody, D430044G18Rik antibody, RGD1309038 antibody, SH3 domain and tetratricopeptide repeats 2 antibody, SH3TC2 antibody, Sh3tc2 antibody
    背景

    Synonyms: KIAA1985, CMT4C, D430044G18Rik, FLJ13605, MNMN, PP12494, RGD1309038, S3TC2_HUMAN, SH3 domain and tetratricopeptide repeats-containing protein 2, SH3TC2.

    Background: SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1,288 amino acid protein that contains one SH3 domain and eight TPR repeats. The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, suggesting a possible function in myelination and/or in regions of axoglial interactions. The SH3TC2 protein is expressed in adult heart, testis, spinal cord, and brain as well as in fetal brain and liver. Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene. Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene. Existing as four alternatively spliced isoforms and containing 18 exons, the SH3TC2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q32.

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