STXBP6 抗体 (AA 1-100) (Cy5)
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- 抗原 See all STXBP6 抗体
- STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STXBP6 antibody is conjugated to Cy5
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Amisyn
- 亚型
- IgG
- Top Product
- Discover our top product STXBP6 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- STXBP6 (Syntaxin Binding Protein 6 (Amisyn) (STXBP6))
- 别名
- Amisyn (STXBP6 产品)
- 别名
- MGC68796 antibody, zgc:86678 antibody, wu:fd20e06 antibody, amisyn antibody, hspc156 antibody, MGC88977 antibody, STXBP6 antibody, LOC100226852 antibody, BC024598 antibody, C85317 antibody, Amisyn antibody, syntaxin binding protein 6 L homeolog antibody, syntaxin binding protein 6 (amisyn) antibody, syntaxin binding protein 6 antibody, stxbp6.L antibody, stxbp6 antibody, STXBP6 antibody, Stxbp6 antibody
- 背景
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Synonyms: Amisyn, HSPC156, STXB6_HUMAN, STXBP6, Syntaxin binding protein 6, Syntaxin-binding protein 6.
Background: Amisyn is a mostly cytosolic protein related to Tomosyn which plays an important role in SNARE complex assembly. Amisyn contains a v-SNARE coiled coil homology domain that binds to Syntaxin 1A and weakly to Syntaxin 4. Three isoforms exist for Amisyn. Isoform 1 is the full length protein, isoform 2 has a different amino acid sequence between residues 204-210 and isoform 3 is missing amino acids 1-102 and contains a different sequence for amino acids 103-150. Amisyn lacks a transmembrane domain and therefore is unable to assemble into a functional, membrane-anchored SNARE complex. This suggests that Amisyn may instead be acting to maintain SNARE conformation and facilitate the binding of VAMP-2. Amisyn can inhibit exocytosis independent of Syntaxin binding.
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